KNG1 CLIA Kit for Bovine(Bos taurus) | EIAab.comKNG1 CLIA Kit for Bovine(Bos taurus)

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KNG1 (Gene name),

Kininogen-1 (Protein name ), KNG1_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

KNG1;

Protein name:

Kininogen-1;

Alternative:

Thiol proteinase inhibitor;Kininogen I;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

N/A

Function:

(1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.

Subcellular Location:

Secreted extracellular space

Protein Attributes:

Sequence length:

621

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

621:

GVNPTVEMKE | SHDFDLVDAL | L

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P01044

UniGene:

Bt.4210

KEGG:

bta:280833

Pfam:

PF00031

Uniprot:

P01044

FOR

ELISA Kit for Bovine Kininogen-1

Cat.:

E1805r

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Packing:

96T

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ELISA Kit for Bovine Kininogen-1

Cat.:

E1805b

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96T

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ELISA Kit for Bovine Kininogen-1

Cat.:

E1805h

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96T

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ELISA Kit for Bovine Kininogen-1

Cat.:

E1805m

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Packing:

96T

CLIA Kit for Bovine Kininogen-1

Cat.:

U1805h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Bovine Kininogen-1

Cat.:

U1805b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Bovine Kininogen-1

Cat.:

U1805r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine Kininogen-1

Cat.:

U1805m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Bovine Kininogen-1

Cat.:

P1805Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine Kininogen-1

Cat.:

P1805Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine Kininogen-1

Cat.:

P1805Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Bovine Kininogen-1

Protein for Bovine Kininogen-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A single gene for bovine high molecular weight and low molecular weight kininogens."
Kitamura N. , Takagaki Y. , Furuto S. , Tanaka T. , Nawa H. , Nakanishi S.
Nature305:545-549(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM HMW)
2.

"Primary structures of bovine liver low molecular weight kininogen precursors and their two mRNAs."
Nawa H. , Kitamura N. , Hirose T. , Asai M. , Inayama S. , Nakanishi S.
Proc. Natl. Acad. Sci. U.S.A.80:90-94(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LMW)
3.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM HMW)
strain: Hereford.
tissue: Fetal liver.
4.

"Bovine high molecular weight kininogen. The amino acid sequence, positions of carbohydrate chains and disulfide bridges in the heavy chain portion."
Sueyoshi T. , Miyata T. , Hashimoto N. , Kato H. , Hayashida H. , Miyata T. , Iwanaga S.
J. Biol. Chem.262:2768-2779(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-378;GLYCOSYLATION AT ASN-87; THR-136; ASN-168; ASN-169; ASN-197 AND ASN-204
5.

"Studies on the structure of bovine kininogen: cleavages of disulfide bonds and of methionyl bonds in kininogen-II."
Kato H. , Nagasawa S. , Suzuki T.
J. Biochem.67:313-323(1970) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 378-393
6.

"Studies on the primary structure of bovine high-molecular-weight kininogen. Amino acid sequence of a fragment ('histidine-rich peptide') released by plasma kallikrein."
Han Y.N. , Komiya M. , Iwanaga S. , Suzuki T.
J. Biochem.77:55-68(1975) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 458-498

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